Optimizar WordPress + Plesk + nginx

1. Activar en plesk nginx
2. En plesk ir al dominio
3. ir a Configuración de Apache y nginx 
4. desactivar  Modo proxy  
5. añadir en Directivas adicionales de nginx el siguiente codigo

if (!-e $request_filename) {
set $test P;
}
if ($uri !~ ^/(plesk-stat|webstat|webstat-ssl|ftpstat|anon_ftpstat|awstats-icon|internal-nginx-static-location)) {
set $test "${test}C";
}
if ($test = PC) {
rewrite ^/(.*)$ /index.php?$1;
}

# GZIP Compression
gzip on;
gzip_disable "MSIE [1-6]\\.(?!.*SV1)";
gzip_min_length 1100;
gzip_buffers 4 32k;
gzip_proxied any;
gzip_comp_level 9;
gzip_types text/plain text/css application/javascript application/x-javascript text/xml application/xml application/xml+rss text/javascript image/x-icon image/bmp image/svg+xml;
gzip_vary on;

# NGINX Caching
location ~* \.(?:ico|css|js|gif|jpe?g|png|svg|woff)$ {
    expires 30d;
    add_header Cache-Control "public";
    log_not_found off;
}

location ~* \.(jpg|jpeg|gif|png)$ {
    expires 365d;
    log_not_found off;
}

location ~* \.(pdf|css|html|js|swf)$ {
    expires 2d;
    log_not_found off;
}

location ~ \.css {
    add_header  Content-Type    text/css;
}
location ~ \.js {
    add_header  Content-Type    application/x-javascript;
}

# SECURITY
location ~* wp-config.php { deny all; }
location ~* "^/wp-content/(?!plugins/).*\.php" { deny all; }




Ahora ir a Configuración de PHP

memory_limit   = 200M
max_execution_time  = 15
post_max_size = 16M
upload_max_filesize =16M
opcache.enable  = on


Y listo, Wordpress volará


No olvides complementar con buenos caches de WordPress, de preferencia que ulticen APC y MemCache para mejorar su desempeño